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The reaction product, N-Hcy-Lys, was purified by HPLC using a reverse phase X Bridge Prep C18 preparative column (19 100 mm, 5 m) from Waters (Milford, MA, USA)

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The authors of the study collected urine and blood specimens from the participants and performed MRS scans on their brains prior to the first dose of sulforaphane and within four hours of the final dose