In states of obesity and aging, NNMT is often overexpressed, leading to the excessive methylation and excretion of nicotinamide
I am almost ending month one, I am loving the appetite suppressant from it and energy from the B12
That said, B Complex injections are generally very safe when administered under medical supervision
Reconstitute a 5 mg vial with 2 mL bacteriostatic water (so 0.1 mL = 250 mcg), refrigerate, and inject at the same time daily for consistency
5-Amino-1MQ is a substrate-mimetic inhibitor that occupies the nicotinamide binding site, with a reported IC of 1.2 0.1 M (Neelakantan et al., J Med Chem, 2017)
However, this difference was not statistically significant (p=0.270)