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To investigate the efficacy of semaglutide on the metabolic and inflammatory features, post-baseline changes were analyzed using an MMRM, with baseline diabetes status, baseline fibrosis stage and diabetes-by-fibrosis interaction as factors (HbA1c, fasting plasma glucose, homeostatic model assessment of insulin resistance, adipose tissue insulin resistance and non-high-density lipoprotein cholesterol could not be included in the diabetes-by-fibrosis interaction as factors) and baseline body weight and baseline value of the feature as covariates, all nested within visit

Microvascular Dysfunction : High blood sugar levels damage the tiny blood vessels that nourish nerves, which restricts the supply of oxygen and nutrients, contributing to nerve degeneration and low oxygen levels in the nerves (72, 73)

[26] Measuring active vitamin B12 (holoTC) levels may offer better diagnostic accuracy than total serum B12 levels when screening for deficiency

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Yeast infections are typically treated with antifungal medications