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Long-term clinical effects of epalrestat, an aldose reductase inhibitor, on diabetic peripheral neuropathy: the 3-year, multicenter, comparative Aldose Reductase Inhibitor-Diabetes Complications Trial

The follow-up time ranges from 1.5 to 60 months

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Many patients notice the slowdown in the first 24 weeks

Reason #3: Rapid weight loss can temporarily disrupt fertility When youre losing weight quicklyespecially 2+ pounds per weekyour hormones undergo significant shifts

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