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Anti-Ro52 autoantibodies from patients with Sjgrens syndrome inhibit the Ro52 E3 ligase activity by blocking the E3/E2 interface

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In our clinical experience, patella tendon tears can result from a range of causes, including: Sudden, high-impact movements: Forceful quadriceps contractions during jumping, sprinting, or abrupt direction changes can overload the tendon

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