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The protective effect of SFN appears to be NRF2-dependent, as NRF2 deficiency exacerbated psoriasis-like symptoms, as well as the inflammatory response and abnormal proliferation of keratinocytes in the mice, and SFN had little therapeutic effect in the IMQ-modeled knockout mice

Although sequence alignment of gB of different human infecting herpesviruses (HSV-1, HSV-2, VZV, HCMV, EBV, KSHV, HHV-6 and HHV-7) showed only low conservation of the bound epitope across subfamilies (Supplementary Fig

Evaluation of poly (2-oxazoline) derivatives as poly (ethylene glycol) alternatives, Master Thesis, Ghent University, 2012

The focus is on reducing inflammation and addressing the underlying causes of the autoimmune response