The nonproductive methylation of glycine to sarcosine, which is physiologically inert, allows an alternative demethylation of SAM (Fig
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A 2019 review by Gwyer and colleagues published in Cell and Tissue Research pulled together the preclinical work on musculoskeletal soft tissue and found consistent acceleration of tendon, ligament, and muscle healing across multiple rodent studies (Gwyer et al., 2019)
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