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Morgan analysts anticipate US GLP-1 drug users will more than double to 25 million by 2030, up from 10 million in 2025

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Established pharmacological options including acamprosate, naltrexone, and nalmefene remain the evidence-based first-line treatments

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Based primarily on preclinical studies with limited human confirmation, GLP-1 receptors appear enriched in regions involved in autonomic control, feeding behavior, reward processing, and cognitive function