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2.2 Eligibility criteria Inclusion criteria: Study design: Randomized controlled trials (RCTs) with either placebo or active comparator arms

( 353a(b)(2)) The related guidance, which extensively covers inordinate and regular compounding (on pp

47 Studies have shown that GLP-1 receptor agonists can improve how mitochondria work and keep the outer mitochondrial membrane stable, which lowers oxidative stress and protects neurons after an injury

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See Retatrutide Side Effects (Australia) for protocol-design implications and the broader GLP-1 Side Effects Cross-Compound Profile for class-level context