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Tryptophan metabolites, such as 5-hydroxytryptamine and 3- hydroxyanthranilic acid, act as potential radical-trapping antioxidants and can protect cells from ferroptosis by eliminating lipid peroxidation [49]

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The correlation between the general health status of the patients, as expressed by their ASA classification, and the oxidative stress parameters (Wilcoxon rank sum test, 1 sided) was evaluated: the group of patients with higher oxidative stress levels were not graded higher on the ASA scale than the group with normal values