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10.1093/pcp/pcd035 90 SmithI

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Modulation of Gene Expression in Human Breast Cancer MCF7 and Prostate Cancer PC3 Cells by the Human Copper-Binding Peptide GHK-Cu

Pattern hair loss is driven by hormonal and genetic factors that GHK-Cu does not address directly

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Since our proteomic study suggested mitochondrial alterations following HC treatment, and considering the recent hypothesis of Simeone (Simeone, 2025) that HC might interact with key cellular antioxidant systems, mitochondrial function was further investigated through oxygen consumption rate (OCR), extracellular acidification rate (ECAR), mitochondrial membrane potential, mitochondrial network morphology, ROS production and GSH/GSSG ratio