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GLP-1 is claimed to have antioxidant activity due to activation of Foxo3a signaling after the up-regulation level and its receptor

While these findings are promising, the complexity of human neurodegenerative diseases and the limitations of animal models necessitate cautious interpretation pending clinical validation

Future studies should explore the dynamic interactions among SIRT1, mTOR, autophagy, and endoplasmic reticulum (ER) stress to elucidate its regulatory functions under varying metabolic states, guiding the development of targeted interventions for early-stage MASLD-related metabolic disorders

Traditional two-dimensional (2D) cell cultures have long been the cornerstone of AD research (Guido et al., 2023)

In the current study, a highly significant decrease in the relative blood viscosity and pronounced elevation in the dielectric constant, dielectric loss and conductivity of kidney tissue were recorded in rats treated with MTX and HPE compared with the MTX rats