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In conclusion, PCs exert significant protective effects on the pathogenesis of GDM by enhancing insulin sensitivity, lowering levels of inflammatory factors, and alleviating liver inflammation, while effectively regulating glucose metabolism during pregnancy and postpartum stages

These interventions appear to enhance each other through overlapping but distinct physiological pathways, creating what researchers term a synergistic effect

The HPC analyzed whether patients prescribed a GLP-1 medication had a previous or current diagnosis of diabetes, overweight/obesity, both, or neither

Efficacy and Safety of Glucagon-Like Peptide-1 Receptor Agonists on Body Weight and Cardiometabolic Parameters in Individuals With Obesity and Without Diabetes: A Systematic Review and Meta-Analysis

Once youve adjusted to it typically after 4 to 6 weeks and arent experiencing severe side effects, berberine may be added gradually

They work best as part of a comprehensive weight management program that includes a balanced diet, regular exercise, and lifestyle modifications