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Liu et al., 2021b)

There is also a theoretical possibility of more pronounced cardiovascular effects, though this remains speculative as semaglutide is generally well-tolerated from a cardiac perspective

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Proinflammatory cytokines, such as TNF-, IL-6, IL-1, and various chemokines, contribute to this process by promoting immune cell infiltration and muscle breakdown via nuclear factor-kappa B signaling [56]

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