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This is why two patients on identical doses can have vastly different outcomes

"The ARCOS data is what I call the Rosetta Stone of the opioid crisis

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This is not ordinary tiredness, but a profound weakness that persists despite adequate rest

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The efficacy and safety of weekly semaglutide (2.4 mg) for the treatment of overweight and obesity was investigated in the Semaglutide Treatment Effect in People with Obesity (STEP) programme, which included individuals with overweight (BMI 27 kg/m 2 ) and complications, including dyslipidaemia, hypertension, sleep apnoea, cardiovascular disease and type 2 diabetes, or individuals with obesity (BMI 30 kg/m 2 ) with or without complications [26, 34,35,36,37,38,39]