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DOI: Published online: May 1, 2025 1 Division of Endocrinology and Metabolism, Department of Internal Medicine, Seoul National University Hospital, Seoul, Korea 2 Department of Internal Medicine, Seoul National University College of Medicine, Seoul, Korea Corresponding author: Jae Hyun Bae Department of Internal Medicine, Seoul National University Hospital, 101 Daehak-ro, Jongno-gu, Seoul 03080, Korea E-mail: [email protected] Copyright 2025 Korean Diabetes Association This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License ( which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited

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GLP-1 has a remarkably short half-life of approximately 1.5 to 2 minutes in circulation due to rapid degradation by the enzyme dipeptidyl peptidase-4 (DPP-4)

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13.2 Ophthalmic ointments Ophthalmic ointments offer significant advantages in managing ocular conditions, particularly for hydrolytically unstable and pH-sensitive pharmaceutical ingredients, including herbal compounds

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