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Ltx1, a mouse locus that influences the susceptibility of macrophages to cytolysis caused by intoxication with Bacillus anthracis lethal factor, maps to chromosome 11
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Naltrexone blocks opioid receptors in the brain's hunger centers, while bupropion increases dopamine and norepinephrine activity to reduce appetite and boost metabolism
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doi: 10.1038/ng.3693