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These agonists effectively mimic the glucose-lowering and weight-loss effects of endogenous GLP-1
This hormone regulates appetite, slows digestion, and helps control blood sugar levels
Injectable administration is generally preferred when maximizing potency, dosing precision, and consistent therapeutic response is the primary goal
Both are typically administered subcutaneously for systemic effects
Semaglutide 2.4 mg (Wegovy) and tirzepatide (Zepbound) are approved for adults with obesity (BMI 30 kg/m) or overweight (BMI 27 kg/m) with at least one weight-related comorbidity
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