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The subsistence of a basal GSH transport despite the disability to confer resistance to drugs co-transported with GSH in chimera M6 and M8 suggests that the two activities can be decoupled, and the transporters remain active

The side effect profiles of these two compounds are dramatically different, and for some people, that difference tips the scale

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Oxidative stress activates the ASK1-JNK pathway, leading to JNK translocation to mitochondria, further exacerbating mitochondrial damage

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