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Prior CSF studies in NPH also indicate inflammatory activation associated with disease state 61,62 , suggesting that integrated immunemetabolic pathway activity may better capture outcome-relevant biology than isolated inflammatory markers

Habib E, Linher-Melville K, Lin H-X, Singh G

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Depending on the involved loads and direction of force, it can range from a subclinical strain of some annular fibers (whiplash injury) that would be referred to the disc injury type A1 over a traumatic disc herniation (injury type B) to a complete dislocation with separation of the segment, disruption of the annular fibers, longitudinal ligaments, joint capsule and posterior structures (disco-ligamentous complex, DLC) that would be injury type C