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and James, S.J

Hassanein, M., et al

Secondary endpoints Weight loss A difference in weight loss was already seen at M3 (9.2% [3.6] vs

Recent findings It is now recognized that intestinal permeability reflects the combined effects of two distinct routes across tight junctions, which form selectively permeable seals between adjacent epithelial cells, and mucosal damage that leads to nonselective barrier loss

Guidance: Red flags requiring MRI with and without contrast Rapid unexplained weight loss, drenching night sweats, persistent fevers, known cancer histories with bone metastasis risk