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Moreover, reduced organ damage by thrombotic occlusion in the lung has been reported in LPS-induced sepsis due to improvement in microvascular circulation by GLP-1 analogs

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[9] Seek urgent medical attention (call 111, contact your GP urgently, or attend A&E) if you develop: Severe, persistent abdominal pain , particularly if it radiates to the back, as this may indicate pancreatitisa rare but serious adverse effect of GLP-1 agonists

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Obesity and cardiovascular disease: an ESC clinical consensus statement

They are contraindicated in patients with a personal or family history of medullary thyroid carcinoma (MTC) or multiple endocrine neoplasia syndrome type 2 (MEN 2)