Berberine has demonstrated anti-inflammatory and antioxidant properties and current research is focusing on its potential for use with diabetes, obesity, PCOS, and fertility, to name a few (2)
Winner for cardiovascular health: Too early to call
The 4 mg strength is typically used after a starter dose of 1.5 mg, before moving up to the maintenance dose (which may be 4 mg or 9 mg depending on the individual)
Additionally, a 2022 meta-analysis in the Journal of Food Biochemistry of studies on cinnamon as an anti-obesity agent found that cinnamon supplementation significantly decreased body weight
J Neurosci 31(17):65876594 Hansen HH, Barkholt P, Fabricius K, Jelsing J, Terwel D, Pyke C, Knudsen LB, Vrang N (2016) The GLP-1 receptor agonist liraglutide reduces pathology-specific tau phosphorylation and improves motor function in a transgenic hTauP301L mouse model of tauopathy
No, current UK guidance recommends a risk-stratified approach rather than routine cessation