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FAO flux analysis using [U- 13 C]PA ( m + 16) FAO activity was measured by tracking the conversion rate of [U- 13 C]PA ( m + 16) to [2- 13 C]citrate ( m + 2) and [2- 13 C]malate ( m + 2) 53

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Indeed, UBX0101 treatment on aged mice with post-traumatic OA after surgery reduces the presence of senescent cells, improves articular cartilage, and upregulates the expression of genes involved in new cartilage growth 25

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