5-Amino-1MQ is a small-molecule competitive inhibitor of nicotinamide N-methyltransferase (NNMT), an enzyme that catalyzes the methylation of nicotinamide using S-adenosyl methionine (SAM)
Contraindications include epilepsy, severe renal impairment, and known hypersensitivity to the compound
Although extremely rare, hydroxocobalamin injections can also cause serious side effects such as a major allergic reaction or irregular heartbeats (palpitations)
It's a surprisingly passive process
By keeping peptide production closer to home, we can better control product standards, reduce reliance on uncertain imported inventory, and provide Canadian researchers with a more transparent and reliable source for research peptides
124 Dendrimer-based nanocarriers were also recently shown to penetrate full-thickness cartilage explants, and be retained in a native joint environment