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OPTIONS Study Phase 2b results announcement (AOD-9604 development terminated)

The rationale for stacking is that different peptides operate through different mechanisms and do not typically compete or interfere with each other when used at standard doses

Metabolism Boosting While AOD9604 may subtly improve energy usage, it doesnt supercharge metabolic rate

AOD 9604 + GHK-Cu When body recomposition is the goal and skin quality or tissue repair is also a priority, AOD 9604 has been stacked with GHK-Cu in investigational settings

However, the largest 24-week trial with 536 participants failed to show statistically significant weight loss, which led to development termination

What is missing There is no published human pharmacokinetic study of subcutaneous AOD-9604, no published human topical or intranasal exposure data, no Phase 3 efficacy trial, no long-term safety data beyond 24 weeks, and no published human cartilage or joint outcome data