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3E), whereas ELISA revealed reduced CST3 levels in these groups compared with uninfected controls (Supplementary Fig

Cuprizone-induced demyelination in animals is accepted for studying multiple sclerosis-related lesions and is characterized by degeneration of oligodendrocytes more than by a direct attack on the myelin sheet (12)

Alpha-MSH is primarily thought to impact melanocytes, dermal cells, and hair follicle cells, which are considered to be responsible for pigmentation

Overall Safety and Tolerability Assessment The primary safety conclusion from the comprehensive trial program was unambiguous: AOD-9604 displayed a very good safety and tolerability profile indistinguishable from placebo

Nausea may increase during the first week at this new dose

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