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COMPARISON WITH RESMETIROM AND THE CASE FOR COMBINATION STRATEGIES Resmetirom, an orally active, liver-directed thyroid hormone receptor- (THR-) agonist, has recently shown positive phase 3 trial results in patients with MASH and F1-F3 fibrosis, improving both MASH resolution and fibrosis compared with placebo
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How does Tirzepatide Work In addition to its glucose-lowering effects, tirzepatide has been associated with significant weight loss in clinical trials
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