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Stubbs RJ et al

Collectively, these findings establish ROS as critical enablers of HCC metastasis, orchestrating EMT, proteolytic matrix degradation, and distant organ colonization through coordinated activation of ERK/AKT, JNK, and NF-B signaling [91], thereby providing a mechanistic basis for the link between oxidative stress and poor clinical outcomes in HCC

Am J Hematol 94(3):E78E80

To determine the right dosage, researchers should consult established, peer-reviewed protocols that align with their specific experimental needs