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GLUT4 is found in insulin-responsive tissues such as heart, adipose tissue, and skeletal muscle

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Specifically, the peptide downregulates inflammatory genes including interleukin-1, tumor necrosis factor-, and nuclear factor-B, while upregulating protective genes such as those encoding antioxidant enzymes, DNA repair proteins, and extracellular matrix components

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The modulation of Nrf2 and NF-B signaling pathways by isothiocyanates is especially relevant to the prevention of cancer because both oxidative stress and inflammation are significant contributors in the development and progression of cancer

Animal studies show epitalon increases the activity of superoxide dismutase (SOD), glutathione peroxidase, and catalase in aging rats