Enzymatic cleavage of albumin results in less efficient FcRn-mediated rescue from lysosomal degradation and, consequently, a dramatically shorter plasma half-life of 3.5 days in humans 60
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According to the American Academy of Ophthalmology (AAO), NAION symptoms include: The AAO has highlighted the need for further research into the connection between these medications and NAION, urging patients to be vigilant about any changes in their vision