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By blocking NNMT, 5-Amino-1MQ drives several metabolic benefits: Boosts NAD Levels Inhibiting NNMT preserves more nicotinamide for NAD synthesis, leading to enhanced mitochondrial function, increased cellular energy output, and activation of sirtuins , the proteins involved in longevity and DNA repair

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doi: 10.3390/diseases12010014 45 DruckerDJ

They found that it attaches to special sensors on cells, called receptors, in a way that is similar to a natural hormone called amylin, which helps control appetite