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Weight fluctuations, sun exposure, and lifestyle factors can accelerate this decline

As neurological and medical complications after stroke are not properly predicted, prevented, or dealt with, they are considered to constitute the main cause of the high morbidity and mortality associated with strokes (78)

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Subsequently, the IL-10 receptor/STAT3 signaling pathway in microglia is autocrinally activated, thereby promoting the expression and release of -endorphin, the latter acts on -opioid receptors on neurons to produce analgesic and neuroprotective effects (103105)