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For purposes of estimating outlier payments for CY 2026, we used the hospital-specific overall ancillary CCRs available in the April 2025 update to the Outpatient Provider-Specific File (OPSF)

As discussed in further detail in section XIII.E

are shareholders of Septerna Inc

The agency announced plans to restrict GLP-1 ingredients intended to be used in these compounded medications

Initial weight loss can be achieved through less expensive and intensive medications

In contrast, no statistically significant differences in body weight were observed between the NC group and the GLP-1RAs@NPs-WYRGRL group or the MNs/GLP-1RAs@NPs-WYRGRL group (Fig