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Underuse of GLP-1 receptor agonists in the management of type 2 diabetes despite a favourable benefit-safety profile
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To obtain crystals of the AsA-bound protein, Cys20-mutated OsDHAR (C20S) was used, which lacks reductase activity but exhibits AsA binding activity
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5-Amino-1MQ is a small molecule inhibitor of nicotinamide N-methyltransferase (NNMT), an enzyme that plays a central role in NAD+ metabolism and cellular energy balance
