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The Conference further underscores that vitamin D supplementation has no proven hard-outcome benefit in CKD, but this should not be misread as a reason to leave deficient patients untreated

Diverse strategies have emerged to modulate ROS in wound healing, namely the use of antioxidant materials such as N -acetyl-l-cysteine (NAC) 172 or enzymes which either increase local perfusion such as glucose oxidase, or clear free radicals through SODs 173,174