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FDAs current compounding-safety page notes concerns for BPC-157 involving peptide-related impurities and active pharmaceutical ingredient characterization in the compounding context [17]

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In the STEP clinical trials, semaglutide 2.4 mg (Wegovy) demonstrated average weight loss of approximately 15% of initial body weight over 68 weeks when combined with lifestyle interventions

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Consumers should be skeptical of any over-the-counter product marketed as a GLP-1 supplement that suggests it can act like a prescription drug, replace a GLP-1 medication or treat a disease such as obesity, says Jeff Ventura, a spokesperson for the Council for Responsible Nutrition, which represents the dietary supplement industry