Some studies link GLP-1 use to an increased risk for ocular diseases such as nonarteritic anterior ischemic optic neuropathy (NAION), diabetic retinopathy, papillitis, and optic nerve disorders
Al-Serri A, Anstee QM, Valenti L et al (2012) The SOD2 C47T polymorphism influences NAFLD fibrosis severity: evidence from case-control and intra-familial allele association studies
Synergistic combined effect of drugs induces cell cycle arrest, apoptosis, and alteration to mitochondrial membrane potential in cancer cells as well as down regulates the expression of CD44 receptor, which are main factor for cancer metastasis
Studies suggest that DM2 accompanied by insulin resistance may contribute to memory impairment and the development of neurodegenerative diseases such as Alzheimers and Parkinsons disease (66)
Chen TK, Knicely DH, Grams ME (2019) Chronic kidney disease diagnosis and management: a review
The toxicity mechanism of A aggregates remains uncertain, but different perspectives exist: 77,128 A might cause AD pathology through the loss of physiological functions during the aggregation process