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Pain 106(12):8189 Schwedt TJ (2014) Chronic migraine

Gastrointestinal adverse effects are among the most commonly reported side effects of GLP-1 therapy, including nausea, vomiting, diarrhoea, and constipation

Axiak-Bechtel SM, Upendran A, Lattimer JC, Kelsey J, Cutler CS, Selting KA, et al

One study has found an association between a genetic variation in the SGLT2 gene (the rs9934336 G-allele) and increased plasma glucose and insulin concentrations during an oral glucose tolerance test [75]

Weight gain has been described during the UKPDS trial in the SUs cohort

Instead, the theory is that bacterial cell components, including cell wall fragments and metabolites, interact with your gut lining and immune cells to produce beneficial effects