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Laron syndrome is a very informative experiment of nature and uncovers the link between low IIS and the related protection from diseases of civilization in contrast to exaggerated IIS induced by Western diet as shown in Figure 1

Milk thistle Milk thistle is an excellent source of an antioxidant called silymarin, which may help prevent glutathione depletion in the liver

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This balance is essential to uphold cellular function and viability, and its disruption links to devastating human diseases