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These differing rates may be in result of variable treatment protocols, different methods of diagnosing recurrence, and inconsistent follow-up

Ploeger BA, Holford NHG

In female mice receiving duloxetine at 140 mg/kg/day (3 times the maximum recommended human dose (MRHD) of 120 mg/day given to children on a mg/m2 basis), there was an increased incidence of hepatocellular adenomas and carcinomas