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Serious but rare adverse effects include pancreatitis, hypoglycaemia when combined with insulin or sulfonylureas, and gallbladder problems

The strengthening the reporting of observational studies in epidemiology (STROBE) statement: guidelines for reporting observational studies

You may notice reduced appetite suppression during the gap, but blood levels will rebuild quickly once you resume

Eur J Pharmacol

Discuss with your prescriber before any significant trip particularly if you're still in dose escalation