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A meta-analysis of three studies including 1,119 participants found that individuals with PAM variants responded less well to GLP-1 receptor agonists and were less likely to lower their HbA1c, a measure of long-term blood sugar

Nat Commun 11(1):1320 Kreitz J, Schnfeld C, Seibert M et al (2019) Metabolic plasticity of acute myeloid leukemia