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Receptors: Established Cell and Whole and Tissue Expression Glucagonlike Peptide1 (GLP- 1) and Receptors After consuming a meal, the L cells of the intestine produce and release the 30 amino acid peptide GLP- 1, which in turn promotes insulin secretion [6]

Rather than reflecting a simple imbalance between energy intake and expenditure, obesity represents an actively defended physiological state in which compensatory mechanisms promote weight regain following weight loss attempts ( Among these strategies, glucagon-like peptide-1 receptor agonists (GLP-1RAs) have emerged as the most effective anti-obesity pharmacotherapies to date

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