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2 Dopaminergic neurotransmission in PD pathogenesis The dopaminergic neurotransmission in PD pathogenesis involves the loss and apoptosis of dopaminergic neurons in the brain, as well as a reduction in dopamine levels, leading to an absolute deficiency of dopamine (15)

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A time-course experiment showed maximal labeling of acetyl-CoA in DKO cells within 2 hours, reaching up to 30% (Supplemental Figure 5A)

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Abstract Purpose of Review Hyperammonemia have significant morbidity and mortality

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