Unlike dietary antioxidants that require external intake, GSH is produced by the body, working alongside compounds like alpha-lipoic acid to maintain balance
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Recently, we used albumin knockout mice and demonstrated that a higher fraction of OTA passes from the blood into hepatocytes and renal tubular epithelial cells resulting in increased levels of toxicity in hypoalbuminemic compared to wild-type mice (Hassan et al
Nguyen, H
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Female Sprague-Dawley (SD) rats, approximately 4 weeks of age, in each group were used for the experiments