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This technique leverages an electrochemical detector (ECD) for dopamine and serotonin, and a fluorescence detector for glutamate, utilizing equipment from reputable companies like Shimadzu Corporation or Agilent Technologies

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After 56 weeks of treatment in EQUIP, body weight reduction from baseline was 10.9%, and 5.1%, with high (15/92 mg), and low (3.75/23 mg), doses of PHEN/TPM, respectively (vs