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These mediators are then internalized and modify enzymatic activity and intracellular metabolism, mimicking the action of insulin

Accessed 9/7/2021, Leslie SW, Siref LE, Soon-Sutton TL, Khan MAB

Refrigeration slows this conversion, maintaining effective preservative concentration closer to the 0.9% starting level through the 28-day window

These studies further revealed that GSH depletion specifically impacted mitochondrial genome stability rather than nuclear genome stability, highlighting the essential requirement for GSH in mitochondrial metabolism

PMCID: PMC3353819