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Stability depends on the peptides specific amino acid sequence, size, and complexity

Bear bile: Dilemma of traditional medicinal use and animal protection

Values ranging from 40 to 120 mg/day (or 80 mg/g creatinine) showed insufficiency, while values over 120 mg/day indicated adequacy in adults

1996 Jun;36(6):357-61

In case of an unbalanced microbiota between good and pathogen micro-organisms (also called dysbiosis), inflammatory conditions will appear and lead to the development of chronic diseases