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Since immune cell trafficking into the CNS is tightly regulated by the blood brain barrier which selectively only allows entry of immune cell subsets required for immune surveillance (80), it remains unknown if CAR-T would efficiently reach senescent cells in the brain parenchyma

Figure 1 BBB Endothelial Cells BECs constitute the innermost luminal component of the BBB (4)

A framework for the aetiogenesis of chronic pancreatitis

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Lebovka, N., Vorobiev, E., & Chemat, F